Thalidomide-O-COOH 是一种基于 Thalidomide 的 Cereblon 配体,可用于募集 CRBN 蛋白。它能够利用 linker 与靶蛋白配体连接,得到 PROTAC 分子。
产品描述
Thalidomide-O-COOH is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. It can be connected to the ligand for protein by a linker to form PROTACs.
Cas No.
1061605-21-7
分子式
C15H12N2O7
分子量
332.268
别名
E3 ligase Ligand 3;Cereblon ligand 3;TCE35031;Thalidomide-O-COOH
储存和溶解度
DMSO:42 mg/mL (126.41 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years