CAS NO: | 102625-70-7 |
规格: | ≥98% |
包装 | 价格(元) |
500mg | 电议 |
1g | 电议 |
2g | 电议 |
5g | 电议 |
Molecular Weight (MW) | 383.37 |
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Formula | C16H15F2N3O4S |
CAS No. | 102625-70-7 |
Storage | -20℃ for 3 years in powder form |
-80℃ for 2 years in solvent | |
Solubility (In vitro) | DMSO: 76 mg/mL (198.2 mM) |
Water:<1 mg/mL | |
Ethanol: 76 mg/mL (198.2 mM) | |
Other info | Chemical Name: 1H-Benzimidazole, 5-(difluoromethoxy)-2-(((3,4-dimethoxy-2-pyridinyl)methyl)sulfinyl)- InChi Key: IQPSEEYGBUAQFF-UHFFFAOYSA-N InChi Code: InChI=1S/C16H15F2N3O4S/c1-23-13-5-6-19-12(14(13)24-2)8-26(22)16-20-10-4-3-9(25-15(17)18)7-11(10)21-16/h3-7,15H,8H2,1-2H3,(H,20,21) SMILES Code: O=S(C1=NC2=CC(OC(F)F)=CC=C2N1)CC3=NC=CC(OC)=C3OC |
Synonyms | BY1023; SKF96022; Protonix; BY 1023; SKF 96022; BY-1023; SKF-96022 |
In Vitro | In vitro activity: Pantoprazole inhibited lysosomal acidification with IC50 value of 194 μM. The pKa values of pantoprazole are 3.83 (pKa1) and 0.11 (pKa2). Besides that, pantoprazole also shows antibacterial effects on Helicobacter pylori. |
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In Vivo | |
Animal model | |
Formulation & Dosage | |
References | Clin Ther. 2000 Nov;22(11):1268-93. |