GSK-2793660 是一种具有口服活性并且不可逆的组织蛋白酶 C (Cathepsin C;CTSC) 抑制剂。GSK-2793660 是一种生物活性肽,可用于支气管扩张的研究。
产品描述
GSK-2793660 is an orally active and irreversible inhibitor of Cathepsin C (CTSC). GSK-2793660 is a bioactive dipeptide that can be used for the research of bronchiectasis [1] [2].
体内活性
GSK-2793660 is a cathepsin C (also known as dipeptidyl peptidase I enzyme) inhibitor in clinical trials for the treatment of cystic fibrosis, non-cystic fibrosis bronchiectasis, anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis and bronchiectasis [1].
Cas No.
1613458-70-0
分子式
C20H27N3O3
分子量
357.45
别名
GSK-2793660
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years