Amifampridine 可用于罕见肌肉疾病的研究。

Amifampridine is predominantly in the treatment of a number of rare muscle diseases. Amifampridine works by blocking potassium channel efflux in nerve terminals so that action potential duration is increased. Ca2+ channels can then be open for a longer time and allow greater acetylcholine release to stimulate muscle at the end plate.

54-96-6

C5H7N3

109.13

阿米吡啶;3,4-Diaminopyridine;3,4-Pyridinediamine;Pyridine-3,4-Diamine;Amifampridine

H2O:24 mg/mL
DMSO:30 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years