COX/5-LO-IN-1 is a cyclooxygenase and 5-lipoxygenase (5-LO) inhibitor, and used for inflammatory and allergic disease states.

COX / 5-LO-IN-1 reduces the biosynthesis of leukotrienes B4, C4, D4 and E4 and cyclooxygenase products (such as prostaglandins and thromboxanes) and can be used to treat inflammation and allergic diseases[1]. COX/5-LO-IN-1 shows inhibitory activities against 5-lipoxygenase(IC50 of 0.2 μM in human whole blood)[2].

154355-75-6

C16H15FN2O2S

318.37

Atreleuton analog;COX/5-LO-IN-1

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years