Tazarotene (AGN190299; trade names Tazorac, Avage, Zorac, and Fabior), a marketed drug, is a third-generation, potent, prescription topical retinoid prodrug used as a cream, gel, or foam for treatment of psoriasis, acne, and sun damaged skin (photodamage).Tazarotene is a member of the acetylenic class of retinoids. Tazarotene is a retinoid prodrug which is converted to its active form, the cognate carboxylic acid of tazarotene (AGN 190299), by rapid deesterification in animals and man. AGN 190299 (“tazarotenic acid”) binds to all three members of the retinoic acid receptor (RAR) RARα, RARβ, and RARγ but shows relative selectivity for RARβ, and RARγ and may modify gene expression. The clinical significance of these findings is unknown.

纯度：≥98%

CAS：118292-41-4