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AHR antagonist 5
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
AHR antagonist 5图片
CAS NO:2247953-39-3
包装:10 mg
市场价:9417元

产品介绍

产品描述

AHR antagonist 5 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist extracted from patent WO2018195397 (example 39; IC50< 0.5 μΜ). It significantly inhibits tumor growth combined with checkpoint inhibitor anti-PD-1.

体内活性

Tumor growth inhibition is statistically significant with AHR antagonist 5 as single. AHR antagonist 5 (10 mg/kg; p.o.; every day for 3 weeks) combination with anti-PD-1 significantly inhibited tumor growth inhibition compared to the anti-PD-1 alone.

Cas No.

2247953-39-3

分子式

C25H27Cl3FN7

分子量

550.89

别名

AHR antagonist 5

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years