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Idramantone
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Idramantone图片
CAS NO:20098-14-0
包装与价格:
包装价格(元)
25 mg电议
50 mg电议
100 mg电议
200 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
Kemantane
伊屈孟酮 (INN)
伊决孟酮
5-Hydroxy-2-adamantanone
产品介绍
Kemantane 是一种免疫激活剂,是 Adamantane 衍生物。

产品描述

Idramantone is an immune agonist.

激酶实验

Assays with human placental aromatase: Microsomes are prepared from human placenta and stored at -80℃. The rate of aromatization is determined by measuring the tritiated water released from [1β-3H]A. The assay is carried out in a final volume of 1 mL, in 10 mM phosphate buffer, pH 7.5, containing 100 mM KCl, 1 mM EDTA, 1 mM dithiothreitol, 100 μM NADPH, the enzyme preparation and the appropriate concentrations of Exemestane (in duplicate) and the substrate. After a 10 min incubation at 37 ℃, the assay is terminated by the addition of 4 mL cold chloroform. The acqueous phase is treated with a charcoal suspension, the supernatant is removed and counted for radioactivity by liquid scintillation in Rialuma. For the determination of the IC50 values, various concentrations of Exemestane are incubated with 20 μg of microsomal protein, in the presence of a fixed amount (50 nM) of [3H]A.

Cas No.

20098-14-0

分子式

C10H14O2

分子量

166.22

别名

Kemantane;伊屈孟酮 (INN);伊决孟酮;5-Hydroxy-2-adamantanone;Idramantone

储存和溶解度

H2O:30 mg/mL (180.5 mM)
DMSO:31 mg/mL (186.5 mM)
Ethanol:31 mg/mL (186.5 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years