Castanospermine 能够抑制α- and β-glucosidases的所有形式。

Castanospermine is a natural compound that inhibits α- and β-glucosidases, especially glucosidase l.

Castanospermine is a potent and specific inhibitor of mammalian and plant α-and β-D-glucosidases in vitro [1].

Experiments in vivo with castanospermine, an inhibitor of the glucosidases that convert protein N-linked high mannose carbohydrates to complex oligosaccharides, resulted in significant inhibition of tumor growth in nude mice [3].

79831-76-8

C8H15NO4

189.21

(1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyindolizidine;1,6,7,8-Tetrahydroxyoctahydroindolizine;栗精胺;亚胺糖栗树精胺;Castanospermine

H2O:32 mg/mL (169.12 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years