N-Formyl-Met-Leu-Phe-Lys 是一种多肽,是选择性FPR1激动剂,作用于 FPR1(IC50:3.5 nM),FPR2(IC50:6.7 nM) 和 FPR2-D2817.32G(IC50:0.88 nM) 。
产品描述
N-Formyl-Met-Leu-Phe-Lys (fMLFK) is a peptide, acts as a potent and selective agonist of FPR1, with EC50s of 3.5 nM, 6.7 μM and 0.88 μM for FPR1, FPR2 and FPR2-D2817.32G, respectively.Chemotactic peptide (fMLFK) binds specifically to receptors on leukocyte membranes. Uptake of chemotactic peptides can contribute to quantitative assessment of neutrophils in localized inflammatory processes and is independent of associated edema formation or microcirculatory compromise.
Cas No.
67247-11-4
分子式
C27H43N5O6S
分子量
565.73
别名
fMLFK;N-Formyl-Met-Leu-Phe-Lys
储存和溶解度
H2O:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years