您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > (3S)-hydroxy Quinidine
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
(3S)-hydroxy Quinidine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
(3S)-hydroxy Quinidine图片
CAS NO:53467-23-5
包装:1 mg
市场价:3981元

产品介绍

产品描述

(3S)-hydroxy Quinidine is an active quinidine metabolite. Quinidine, an antiarrhythmic agent, undergoes rapid first-pass metabolism by the cytochrome P450 (CYP) isoforms CYP3A4, CYP2C9, CYP2E1, and CYP3A5, with CYP3A4 being the most active enzyme in the (3S)-hydroxy quinidine formation. (3S)-hydroxy Quinidine prolongs repolarization of canine Purkinje fibers in vitro and prevents ventricular fibrillation and ventricular tachycardia after coronary reperfusion in isolated rat hearts in a dose-dependent manner.

Cas No.

53467-23-5

分子式

C20H24N2O3

分子量

340.42

别名

(3S)-hydroxy Quinidine

储存和溶解度

Methanol:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years