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Leteprinim
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Leteprinim图片
CAS NO:138117-50-7
包装与价格:
包装价格(元)
1 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议
200 mg电议

产品名称
AIT082 acid
AIT 082 acid
AIT-082 acid
产品介绍
Leteprinim 是一种次黄嘌呤衍生物,可刺激体外神经突生长和星形胶质细胞产生腺苷和神经营养因子。

产品描述

Leteprinim is an hypoxanthine derivative that stimulates in vitro neurite outgrowth and the production of adenosine and neurotrophins from astrocytes.

体外活性

Leteprinim stimulates the outgrowth of neurites from PC12 cells and neurons, stimulates the synthesis and/or release of neurotrophic factors from astrocytes, enhances nerve fibre regeneration in vivo, and enhances memory in animals and humans. Leteprinim also protects against glutamate neurotoxicity in vitro and in vivo, which has led to successful tests of Leteprinim in animal models of acute central nervous system injury[3].

体内活性

Leteprinim (60 mg/kg/day; i.p., for 7 days, starting from 20 min before the kainate injection) did not modify the seizures caused by kainate but, like diazepam, it decreased kainate-induced mortality, the reduction of GAD activity, and the loss of hippocampal neurons in rats[2].

Cas No.

138117-50-7

分子式

C15H13N5O4

分子量

327.29

别名

AIT082 acid;AIT 082 acid;AIT-082 acid;Leteprinim

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years