EIF2α activator 1（Compound 40）是真核生物起始因子2α（eIF2α）磷酸化的激活剂。EIF2α activator 1 增加 EIF2α 下游蛋白 ATF 和 CHOP 表达水平。EIF2α activator 1 对 K562 和 PBMC 细胞具有抗增殖活性，IC50值分别为 4.00 和 19.3 μM。

EIF2α activator 1 (Compound 40) is an activator of eukaryotic initiation factor 2 alpha ( eIF2α ) phosphorylation. EIF2α activator 1 increases the expression level of eIF2α downstream proteins, ATF and CHOP. EIF2α activator 1 exhibits antiproliferative activity againist K562 and PBMC cells with IC 50 s of 4.00 and 19.3 μM, respectively [1].

C25H19F6N3O3

523.43

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years