Disopyramide 是用于研究房性和室性心律失常的 IA 类抗心律失常试剂。它阻断心肌快速内向钠电流，延长心肌动作电位持续时间。它抑制 HERG 编码的钾通道。它也表现出复杂的蛋白质结合，并具有强大的负性肌力作用。

A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.

3737-09-5

C21H29N3O

339.483

Hypaque sodium;Triombrin;amidotrizoate sodium;达舒平;Disopyramide

DMSO:197.4 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years