Pinacidil 是钾通道的有效激活剂。Pinacidil通过打开 K+-通道使血管平滑肌超极化,显示出抗高血压活性。它显著改善再灌注功能和心脏顺应性。它具有直接的心脏保护作用。
产品描述
Pinardil (P-1134, S-1230) is a guanidine that opens potassium channels and directly dilates peripheral blood vessels in small arteries, lowering blood pressure and peripheral resistance and producing fluid retention.
Cas No.
60560-33-0
分子式
C13H19N5
分子量
245.32
别名
吡那地尔;P 1134;P-1134;S 1230;P1134;S-1230;Pinacidil
储存和溶解度
DMSO:100 mg/mL (407.63 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years