IRAK4-IN-16 (compound 4) 是一种强效的白细胞介素 -1 受体相关激酶 4(IRAK4) 抑制剂，IC50为 2.5 nM。IRAK4-IN-16 对 OCI-LY10、TMD8、Ramos 和 HT 细胞表现出细胞毒性活性，其IC50分别为 0.2、0.2、0.6 和 2.7 μM。

IRAK4-IN-16 (compound 4) is a potent inhibitor of interleukin-1 receptor associated kinase 4 (IRAK4) with an IC 50 of 2.5 nM. IRAK4-IN-16 exhibits cytotoxicity activity against OCI-LY10, TMD8, Ramos and HT cells, with IC 50 values of 0.2, 0.2, 0.6, and 2.7 μM, respectively [1].

1812188-83-2

C17H20F2N8O

390.39

IRAK4-IN-16

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years