Ticarcillin disodium 主要用于抗革兰氏阴性菌, 特别是绿脓杆菌, 也是少数可研究嗜麦芽感染的抗生素。

Ticarcillin Disodium is the disodium salt form of ticarcillin, a broad-spectrum, semi-synthetic penicillin antibiotic with bactericidal and beta-lactamase resistant activity. Similar to carbenicillin in action, ticarcillin inactivates the penicillin-sensitive transpeptidase C-terminal domain by opening the lactam ring. This inactivation prevents the cross-linkage of peptidoglycan strands, thereby inhibiting the third and last stage of bacterial cell wall synthesis. This leads to incomplete bacterial cell wall synthesis and eventually causes cell lysis.

4697-14-7

C15H14N2Na2O6S2

428.39

Ticarcillin disodium salt;Ticarpen;替卡西林二钠;Ticarcillin disodium

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years