9(E),11(E)-12-nitro Conjugated linoleic acid (9(E),11(E)-12-nitro CLA) is a nitrated fatty acid. It is formed from 9(Z),11(E)-CLA upon exposure to acidified nitrite, peroxynitrite, gaseous nitrogen dioxide, or a combination of myeloperoxidase, hydrogen peroxide, and nitrite.1It is also formed in LPS-stimulated RAW 264.7 macrophages, an effect that can be reduced by the nitric oxide synthase (NOS) inhibitor L-NAME .29(E),11(E)-12-nitro CLA has been found in human plasma.

1515620-30-0

C18H31NO4

325.44

9(E),11(E)-12-nitro Conjugated Linoleic Acid

DMF:50 mg/mL
Ethanol:50 mg/mL
DMSO:50 mg/mL
0.1 M Na2CO3:1 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years