Fesoterodine 是可口服的，非亚型选择性的竞争性毒蕈碱受体拮抗剂，用于膀胱过度活动症，对 M1、M2、M3、M4 和 M5 受体的pKi值分别为 8.0、7.7、7.4、7.3 和 7.5。

Fesoterodine is an orally active, competitive mAChR antagonist with pKi values of 8.0, 7.7, 7.4, 7.3, 7.5 for M1, M2, M3, M4, M5 receptors, respectively. It is used for the overactive bladder (OAB).

Fesoterodine (0.01-1 mg/kg; i.v.) reduces the micturition pressure and increases bladder capacity and ICIs (intercontraction intervas) at the lowest dose tested of 0.01 mg/kg [3].

286930-02-7

C26H37NO3

411.586

(R) Fesoterodine;弗斯特罗定;Fesoterodine

Ethanol:50 mg/mL (121.48 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years