SJB3-019A is a potent and novel inhibitor of USP1, 5 times more potent than SJB2-043 in promoting ID1 degradation and cytoxicity in K562 cells with IC50 of 0.0781 μM.

SJB3-019A with IC50 of 0.0781 μM is 5 times more potent than SJB2-043 in promoting ID1 degradation and cytoxicity in K562 cells. SJB3-019A increases the levels of Ub-FANCD2 and Ub-PCNA, and decreases the HR activity.

2070015-29-9

C16H8N2O3

276.25

SJB3-019A

DMSO:10 mg/mL (36.20 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years