Anti-MRSA agent 3 (compound 18) 对耐甲氧西林金黄色葡萄球菌 (MRSA)具有较高的抑制活性，MIC为 0.098 μg/ml，并且对正常细胞具有较低的毒性。Anti-MRSA agent 3 对细菌细胞壁和细胞膜具有较强的破坏能力，对细菌基因组 DNA 具有较高的结合亲和力。

Anti-MRSA agent 3 (compound 18) has highly inhibitory activity against Methicillin-resistant Staphylococcus aureus (MRSA) with MIC of 0.098 μg/ml, and low cytotoxicity in normal cells. Anti-MRSA agent 3 has relatively strong ability to destroy bacterial cell wall and membrane, high binding affinity to bacterial genomic DNA [1].

Anti-MRSA agent 3 has potent efficacy at a dose of 10 mg/kg (20% survival) in a mouse peritonitis model [1].

2416909-42-5

C29H18BrN3O2

520.38

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years