GJ103 是通读化合物 GJ072 的活性类似物。一些 GJ072 类似物(例如,GJ103、GJ106、GJ109 和 GJ111)通过 FCATMpSer1981 和 IRIF 测定一致地证明了它们在所有三种 PTC 中的活性。 GJ103 具有与 RTC13 或 RTC14 相似的通读活性,但比 RTC13 和 RTC14 对 A-T 细胞的耐受性更高。
产品描述
GJ103 sodium salt is an active analog of the read-through compound GJ072. Some GJ072 analogs (e.g., GJ103, GJ106, GJ109, and GJ111) consistently demonstrates their activities in all three PTCs by both FCATMpSer1981 and IRIF assays. GJ103 have similar read-through activity as RTC13 or RTC14, but are more tolerable than RTC13 and RTC14 to A-T cells.
Cas No.
1459687-89-8
分子式
C16H14N4O3S
分子量
342.37
别名
GJ103
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years