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LG100754
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
LG100754图片
CAS NO:180713-37-5
包装:50 mg
市场价:21374元

产品名称
UVI 2112
产品介绍

产品描述

LG100754 is an insulin sensitizer that functions through RXR. LG100754 is an RXR dimer modulator. LG100754 acts as an RXR: RXR homodimer antagonist, but functions as an agonist towards RXR: PPARα and RXR: PPARγ heterodimers.

体外活性

LG100754 can also improve TNFα-mediated insulin resistance in mature adipocytes. LG100754 is a selective activator of endogenous RXR heterodimers. LG100754 acts as a bona fide activator of endogenous RXR: PPARγ heterodimers and regulator of insulin-dependent signaling pathways[1].

体内活性

LG100754 (100 mg/kg) fully blocks the enhance in glucose levels. It also shows that LG100754 can improve insulin resistance in vivo[1].

Cas No.

180713-37-5

分子式

C26H36O3

分子量

396.56

别名

UVI 2112;LG100754

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years