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Ginkgolide A(BN-52020)
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Ginkgolide A(BN-52020)图片
CAS NO:15291-75-5
规格:≥98%
包装与价格：
包装价格(元)
10mg电议
25mg电议
50mg电议
100mg电议
250mg电议
500mg电议
1g电议

产品介绍
理化性质和储存条件
Molecular Weight (MW)408.4
FormulaC20H24O9
CAS No.15291-75-5
Storage-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)DMSO: 81 mg/mL (198.3 mM)
Water:<1 mg/mL
Ethanol: 2 mg/mL (4.9 mM)
Other info

Chemical Name: 9H-1,7a-(Epoxymethano)-1H,6aH-cyclopenta(c)furo(2,3-b)furo(3',2':3,4)cyclopenta(1,2-d)furan-5,9,12(4H)-trione, 3-(1,1-dimethylethyl)hexahydro-4,7b-dihydroxy-8-methyl-, (1R,3S,3aS,4R,6aR,7aR,7bR,8S,10aS,11aS)-

InChi Key: FPUXKXIZEIDQKW-VKMVSBOZSA-N

InChi Code: InChI=1S/C20H24O9/c1-7-12(22)26-10-6-17-9-5-8(16(2,3)4)18(17)11(21)13(23)28-15(18)29-20(17,14(24)27-9)19(7,10)25/h7-11,15,21,25H,5-6H2,1-4H3/t7-,8+,9-,10+,11+,15+,17-,18+,19-,20-/m1/s1

SMILES Code: C[C@@H]1C(O[C@@H]2[C@@]1(O)[C@@]34C(O[C@H]5[C@@]3([C@]6([C@@H](O)C(O[C@H]6O4)=O)[C@H](C(C)(C)C)C5)C2)=O)=O

SynonymsBN52020; Ginkgolide A; BN 52020; BN-52020;
实验参考方法
In Vitro

In vitro activity: Ginkgolide A (BN-52020) is a highly active PAF antagonist cage molecule that is isolated from the leaves of the Ginkgo biloba tree. Shows potential in a wide variety of inflammatory and immunological disorders. Ginkgolide A (BN-52020) failed to affect apoptotic damage neither in serum-deprived nor in staurosporine-treated neurons

In VivoGinkgolide A significantly shortened the sleeping time in anesthetized mice
Animal modelMice
Formulation & DosageN/A
References

[1]. Wada, K., et al., Isolation of bilobalide and ginkgolide A from Ginkgo biloba L. shorten the sleeping time induced in mice by anesthetics. Biol Pharm Bull, 1993. 16(2): p. 210-2.

[2]. Ahlemeyer, B. and J. Krieglstein, Pharmacological studies supporting the therapeutic use of Ginkgo biloba extract for Alzheimer's disease. Pharmacopsychiatry, 2003. 36(S 1): p. 8-14.