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MTIC
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
MTIC图片
CAS NO:3413-72-7
包装与价格:
包装价格(元)
1 mg电议
5 mg电议
10 mg电议
25 mg电议

产品名称
NSC 407347
产品介绍

产品描述

MTIC is a DNA alkylating agent, an active metabolite of dacarbazine, and an active degradation product of temozolomide.[1],[2],[3] MTIC is cytotoxic to L-cells and decreases thymidine and uridine uptake by 55 and 65%, respectively, when used at a concentration of 1 mM.[2] It is also cytotoxic to TLX5 murine lymphoma cells in a concentration-dependent manner.[3]

体内活性

In vivo, MTIC induces formation of mammary adenofibromas in rats when administered at a cumulative dose of 890 mg per animal over 14 weeks.[4]

Cas No.

3413-72-7

分子式

C5H8N6O

分子量

168.16

别名

NSC 407347;MTIC;MTIC

储存和溶解度

DMSO:Slightly soluble
Methanol:Slightly soluble,Heated
Powder: -20°C for 3 years
In solvent: -80°C for 2 years