产品描述
2'-Deoxyguanosine 5'-monophosphate (dGMP) is used as a substrate of guanylate kinases to generate dGDP, which in turn is phosphorylated to dGTP, a nucleotide precursor used in DNA synthesis. In addition, dGMP can be efficiently phosphorylated by the type I thymidylate kinase of the malarial agent P. falciparum. In humans, deficiency of mitochondrial deoxyguanosine kinase, which synthesizes dGMP from ATP and deoxyguanosine, contributes to mitochondrial DNA depletion syndrome.
Cas No.
146877-98-7
分子式
C10H14N5Na2O8P
分子量
409.202
别名
2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)
储存和溶解度
PBS (pH 7.2):10 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years