Oxybutynin hydrochloride 是一种抗胆碱能药物，用于缓解泌尿和膀胱困难。它抑制血管 Kv通道，IC50为 11.51 μM。

Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties. It competitively antagonizes the M1, M2, and M3 subtypes of the muscarinic acetylcholine receptor.

Oxybutynin relieves urinary and bladder difficulties, including frequent urination and inability to control urination (urge incontinence), by decreasing muscle spasms of the bladder. Oxybutynin competitively antagonizes the M1, M2, and M3 subtypes of the muscarinic acetylcholine receptor. [1] Oxybutynin also has direct spasmolytic effects on bladder smooth muscle as a calcium antagonist and local anesthetic, but at concentrations far above those used clinically. [2]

1508-65-2

C22H32ClNO3

393.95

盐酸奥昔布宁;Oxybutynin HCl;Oxybutynin hydrochloride;Oxybutynin chloride

Ethanol:73 mg/mL (185.3 mM)
DMSO:73 mg/mL (185.3 mM)
H2O:4 mg/mL (10.15 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years