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Pyributicarb
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Pyributicarb图片
CAS NO:88678-67-5
包装与价格:
包装价格(元)
5 mg电议
50 mg电议
100 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
稗草畏
TSH-888
产品介绍
Pyributicarb 是氨基甲酸酯型除草剂,能够有效激活CYP3A4基因及人类孕烷 X 受体。

产品描述

Pyributicarb is a potent activator of both CYP3A4 gene and human pregnane X receptor (hPXR).

体外活性

Pyributicarb was found to increase the CYP3A4 reporter activity at 0.1 to 1 microM more strongly than typical CYP3A4 inducer rifampicin.?Expression of hPXR-siRNA clearly diminished the pyributicarb-stimulated CYP3A4 reporter activity in 3-1-10 cells and decreased the endogenous CYP3A4 mRNA levels in HepG2 cells.?Pyributicarb caused enhancement of CYP3A4-derived reporter activity in mouse livers introduced with hPXR by adenovirus[1].

Cas No.

88678-67-5

分子式

C18H22N2O2S

分子量

330.45

别名

稗草畏;TSH-888;Pyributicarb

储存和溶解度

DMSO:100 mg/mL (302.63 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years