WJ460 是一种有效的肌铁蛋白抑制剂。 WJ460 在乳腺癌细胞中显示出抗转移活性。

WJ460 is an effective inhibitor of myoferlin. WJ460 exerts anti-metastatic activity in breast cancer cells.

WJ460 dose-dependently blocks breast cancer cell invasion through Collagen I(IC50: 43.37 nM in MDA-MB-231 and 36.40 nM in BT549 cells)[1].

In a spontaneous metastasis model, WJ460 inhibits angiogenesis, breast tumor growth, and spontaneous metastasis [1].

1415251-36-3

C27H28N2O3S

460.59

WJ460

DMSO:200 mg/mL (434.2 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years