AI-10-47 是CBFβ-RUNX结合的小分子抑制剂(IC50:3.2 μM)。

AI-10-47 is a small molecule inhibitor of CBFβ-RUNX binding(IC50 : 3.2 μM).

AI-10-47 significantly inhibits ME-1, TUR, M0-91, THP-1 and U937 cell growt;AI-10-47 with 10 μM weakly inhibits CBFβ-RUNX binding.

1256094-31-1

C13H8F3N3O

279.222

1H-Benzimidazole, 2-(2-pyridinyl)-6-(trifluoromethoxy)-AI-10-47

DMSO:100 mg/mL (358.14 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years