2-Amino-6-cyclopropylamino-9H-purine 是阿巴卡韦(abacavir) 的关键中间体，以氰基乙酸乙酯为原料，经亚硝化、盐酸胍在EtONa存在下环合、还原得到2,4,5-三氨基-6-羟基嘧啶

2-Amino-6-cyclopropylamino-9H-purine,the key intermediate of abacavir was synthesized from ethyl cyanoacetate by nitrosation,cyclization with guanidine hydrochloride in the presence of EtONa and reduction to give 2,4,5-triamino-6-hydroxypyrimidine

120503-69-7

C8H10N6

190.21

DMSO:55 mg/ml (289.15 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years