NUC-3373 是一种胸腺嘧啶合酶抑制剂,属于嘧啶核苷酸类似物,具有抗癌活性。它能诱发宿主免疫反应,有潜力增强免疫治疗。
产品描述
NUC-3373 (Fosifloxuridine nafalbenamide), a pyrimidine nucleotide analogue, is a Thymidylate synthase inhibitor.NUC-3373 has anticancer activity. NUC-3373 is a ProTide transformation of 5-FU that generates much higher concentrations of FUDR-MP in patients' cells.
Cas No.
1332837-31-6
分子式
C29H29FN3O9P
分子量
613.535
别名
NUC-3373;NUC 3373;NUC3373
储存和溶解度
DMSO:100 mg/mL (162.99 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years