Iclaprim 是一种细菌二氢叶酸的选择性新型抑制剂, 可抑制金黄色葡萄球菌的生长, 其MIC90值为 0.06 μg/mL。

Iclaprim is a novel specific bacterial Dihydrofolate inhibitor. It can inhibit the growth of S. aureus (MIC90: 0.06 μg/mL).

Iclaprim, a new selective dihydrofolate inhibitor.?Iclaprim's interaction with a resistant Staphylococcus aureus dihydrofolate reductase (DHFR) is outlined in comparison to trimethoprim (TMP).?This compound is active against methicillin, TMP and vancomycin resistant strains[1].

192314-93-5

C19H22N4O3

354.4

AR-100;艾拉普林

DMSO:28 mg/mL (79 mM),Need ultrasonic and warming
Powder: -20°C for 3 years
In solvent: -80°C for 2 years