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Sari 59-801
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Sari 59-801图片
CAS NO:80565-58-8
包装与价格:
包装价格(元)
1 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议

产品名称
Sari-59-801
产品介绍
Sari 59-801 是具有口服活性的降血糖化合物,能够降低几个物种的血糖,且可以提高大鼠和小鼠的血浆中胰岛素水平。

产品描述

Sari 59-801 is a novel, orally effective hypoglycemic compound that appears to act largely by stimulation of insulin release. SARI-59-801 was more potent in producing hypoglycemia (ED25 = 47 mg/kg) than their lean littermates (ED25 = 131 mg/kg).

体内活性

The 2-hr hypoglycemic ED25 in fasting mice was 110 mg/kg; the plasma insulin levels were increased, with an ED50 of 47 mg/kg. The significant hypoglycemic activity was observed 2 hr after oral administration of 59-801 to fasting rats (ED25 = 86 mg/kg), while plasma insulin was elevated by 62% at 100 mg/kg.

Cas No.

80565-58-8

分子式

C18H23N3O2

分子量

313.39

别名

Sari-59-801

储存和溶解度

DMSO:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years