TP3011 is a potent topoisomerase I inhibitor equipotent as SN38 and is an active metabolite of CH-0793076.

Cell proliferative activities against various human cancer cell lines inhibited by TP3011 (0-100 nM; 72 hours), producing IC50 of cell growth of 0.85 nM; 8.5 nM; and 8.2 nM in HCT116, QG56, and NCI-H460 (NSCLC) cells, respectively[2].

534605-74-8

C26H26N4O5

474.51

CH0793011

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years