MAC glucuronide phenol-linked SN-38 is a pH-susceptible lactone MAC glucuronide phenol-linked SN-38 (DNA topoisomerase I inhibitor) drug linker. MAC glucuronide phenol-linked SN-38 is cytotoxic across L540cy cells and Ramos cells with IC50 values of 113 and 67 ng/mL, respectively[1].

2246380-69-6

C50H54N6O20S

1091.06

DMSO:200 mg/mL (183.31 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years