Nemorubicin 是一种 Doxorubicin 衍生物,具有抗肿瘤活性。它需要完整的核苷酸切除修复系统才能发挥活性。它对多药耐药表型的多种肿瘤细胞系具有细胞毒性。
产品描述
Nemorubicin is a doxorubicin derivative that differs significantly from its parent drug in terms of spectrum of antitumor activity, metabolism and toxicity profile. The drug is active on tumors resistant to alkylating agents, topoisomerase II inhibitors and platinum derivatives.
Cas No.
108852-90-0
分子式
C32H37NO13
分子量
643.642
别名
PNU 152243;Methoxymorpholinyldoxorubicin;奈莫柔比星;PNU-152243A
储存和溶解度
DMSO:45 mg/mL (69.91 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years