DBIBB 是一种溶血磷脂酸 (LPA2) 的 2 型 G 蛋白偶联受体的特异性非脂质激动剂,可减轻胃肠道辐射综合征,增加肠隐窝存活率和肠细胞增殖,减少细胞Apoptosis" style="display: inline; color: #c13a36">凋亡 (Apoptosis)。DBIBB 是一种能够缓解高剂量 γ 射线对造血和胃肠系统引起的急性放射综合征的候选药物。
产品描述
DBIBB is a specific nonlipid agonist of the type 2 G protein coupled receptor for lysophosphatidic acid (LPA2). DBIBB mitigates the gastrointestinal radiation syndrome, increases intestinal crypt survival and enterocyte proliferation, and reduces apoptosis. DBIBB represents a drug candidate capable of mitigating acute radiation syndrome induced by high-dose γ-radiation to the hematopoietic and gastrointestinal system [1].
Cas No.
1569309-92-7
分子式
C23H20N2O6S
分子量
452.48
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years