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Hematein
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Hematein图片
CAS NO:475-25-2
包装与价格:
包装价格(元)
50 mg电议
1 mL*10 mM(in DMSO)电议

产品介绍

产品描述

Hematein inhibits Akt/PKB Ser129 phosphorylation, the Wnt/TCF pathway, and increases apoptosis in lung cancer cells. Hematein is an oxidation product of hematoxylin acted as a dye and it also is an allosteric casein kinase II inhibitor (IC50: 0.74 μM).

体外活性

Hematein (50 and 100 μM; 48 hours) inhibits CK2-specific Akt phosphorylation. Hematein (50 and 100 μM; 48 hours) causes apoptosis in A427 lung cancer cells. Hematein (10-100 μM; 14 days) inhibits cell growth in A427 lung cancer cells [1].

体内活性

In A427 lung cancer cell xenografts, Hematein (intraperitoneal injections; 50 mg/kg; twice a week for 6 weeks) inhibits tumor growth[1].

Cas No.

475-25-2

分子式

C16H12O6

分子量

300.26

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years