SU1498 是一种选择性的 VEGFR2 抑制剂，能够抑制 Flk-1 (IC50:700 nM)。

SU 1498 is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2 (VEGFR2, aka FLK1; IC50 = 700 nM), having negligible activity at several other serine/threonine and tyrosine kinases.1, 2 It effectively blocks signaling through VEGFR2 both in vitro and in vivo.1, 3 SU 1498 is used to study the role of VEGFR2 signaling in diverse processes, including angiogenesis, tumor growth, neural progenitor cell survival, and neuroregeneration.

168835-82-3

C25H30N2O2

390.527

Tyrphostin SU 1498;AG 1498

DMSO:150 mg/mL (384.10 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years