2'-Deoxyuridine 5'-monophosphate disodium salt 能够被双底物酶胸苷酸合酶 (TS) 还原甲基化为 dTMP (2'-deoxythymidine 5'-monophosphate)。其中 dTMP 是 DNA 合成所需的核苷酸。

2'-Deoxyuridine 5'-monophosphate (dUMP) is used by the enzyme thymidylate synthetase (TS) for the de novo production of dTMP. dUMP is used as the reference substrate in studies of dUMP analogues in potential chemotherapy applications.

42155-08-8

C9H11N2Na2O8P

352.146

2'-dUMP·2Na;2-脱氧尿嘧啶核苷-5'-单磷酸二钠盐;2'-脱氧尿苷-5'-单磷酸二钠;2'-Deoxyuridine 5'-monophosphate disodium salt

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years