NSC139021 是一种具有高度选择性的ERG阳性癌细胞生长抑制剂，抑制不同细胞系的IC50值为 30-400 nM。

NSC139021 is a Rio2 kinase (RIOK2) inhibitor that inhibits ERG protein.

NSC139021 selectively inhibits growth of ERGpositive cancer cell lines with minimal effect on normal prostate or endothelial cells or ERG-negative tumor cell lines.?The IC50 of NSC139021 for cell growth inhibition of responsive cell lines range between 30 nM to 400 nM[1].

1147-56-4

C13H9N3OS

255.3

ERGi-USU;1-(2-噻唑基偶氮)-2-萘酚

DMSO:62 mg/mL (242.85 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years