Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III) is an inducer of ferroptosis.1 It induces ferroptosis, but not apoptosis or necroptosis, in NB1 cancer cells when used at a concentration of 3 μM.1 Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III) inhibits proliferation of BJAB, NALM-6, Jurkat, MelHO, and MCF-7 cancer cells (IC50s = 0.07, 2.5, 1.5, 3, and 5 μM, respectively), as well as NALM-6 cells resistant to daunorubicin and vincristine when used at concentrations ranging from 0.04 to 0.125 μM.2

39916-28-4

C20H14ClFeN2O2

405.64

DMF:20 mg/mL
Ethanol:0.3 mg/mL
DMSO:14 mg/mL
PBS (pH 7.2):Partially Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years