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Fosravuconazole L-lysine ethanolate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Fosravuconazole L-lysine ethanolate图片
CAS NO:914361-45-8
包装与价格:
包装价格(元)
2 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议
200 mg电议

产品名称
E-1224 L-lysine ethanolate
BMS-379224 L-lysine ethanolate
产品介绍
Fosravuconazole L-lysine ethanolate 是一种口服广谱抗真菌剂,是Ravuconazole 的前药,可研究念珠菌病,灰指甲病和寄生虫病。

产品描述

FosravuconazoleL-lysine ethanolate is a broad-spectrum antifungal agent. In Japan, it is approved for the treatment of onychomycosis, a fungal infection of the nail. It is a prodrug that is converted into ravuconazole.

体外活性

Fosravuconazole has potent in vitro antifungal activity against a wide range of fungal species such as Candida, Aspergillus, and Trichophyton species[1].

体内活性

Fosravuconazole (E-1224; 10-50 mg/kg; oral administration; daily; for 20 days) treatment suppresses the parasitemia and prevents death in mice infected with the T. cruzi Y strain[2].

Cas No.

914361-45-8

分子式

C31H40F2N7O8PS

分子量

739.73

别名

E-1224 L-lysine ethanolate;BMS-379224 L-lysine ethanolate

储存和溶解度

DMSO:48mg/mL (64.89mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years