GPI-1485 是一种免疫抑制的特异性亲免蛋白配体,可促进中风后的神经功能改善和神经再生。
产品描述
GPI-1485 (GM1485) is a nonimmunosuppressive immunophilin ligand, promoting neurofunctional improvement and neural regeneration following stroke.
体外活性
GPI-1485 induced cellular reprogramming and neural cell induction in normal human dermal fibroblasts (NHDF) [1].
体内活性
GPI-1485 (5 mg/kg; intraperitoneal injection; 6-week period of daily) improved long-term neurological recovery in rats
Cas No.
186268-78-0
分子式
C12H19NO4
分子量
241.287
别名
GM1485
储存和溶解度
DMSO:95 mg/mL (393.73 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years