Dexpanthenol 是泛酸的生物活性醇,能够导致细胞中辅酶 A 含量升高。
产品描述
Dexpanthenol is an alcoholic analogue of D-pantothenic acid and cholinergic agent. Dexpanthenol acts as a precursor of coenzyme A necessary for acetylation reactions and is involved in the synthesis of acetylcholine. Although the exact mechanism of the actions of dexpanthenol is unclear, it may enhance the effect of acetylcholine. Dexpanthenol acts on the gastrointestinal tract and increases lower intestinal motility. It is also applied topically to the skin to relieve itching and to promote healing.
体内活性
Dexpanthenol has positive effects on protection of cerebral tissue after ischaemia reperfusion[1]. Topical application of dexpanthenol is widely used in clinical practice for the improvement of wound healing. Upregulation of IL-6, IL-1, CYP1B1, CXCL1, CCL18 and KAP 4-2 gene expression and downregulation of psorasin mRNA and protein expression are identified in samples treated topically with dexpanthenol[2].
Cas No.
81-13-0
分子式
C9H19NO4
分子量
205.254
别名
D-Pantothenyl alcohol;Ilopan;D-泛醇;D-泛醇(维生素原B5);Pantothenol;Dexpanthenol
储存和溶解度
DMSO:33 mg/mL (160.78 mM),Need ultrasonic and warming
Powder: -20°C for 3 years
In solvent: -80°C for 2 years