NHE3-IN-3 (Compound 1) 是一种钠/氢交换异构体 3 (NHE3) 抑制剂，对人和大鼠 NHE3 的pIC50分别为 6.2 和 6.6. NHE3-IN-3 在大鼠中具有很高的口服生物利用度 (98%)。

NHE3-IN-3 (Compound 1) is a Na + /H + exchanger isoform 3 (NHE3) inhibitor with pIC 50 of 6.2 and 6.6 against human and rat NHE3, respectively. NHE3-IN-3 shows high (98%) oral bioavailability in Sprague–Dawley rats [1].

543734-50-5

C16H16Cl2N2O2S

371.28

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years