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Scutebarbatine W
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Scutebarbatine W图片
CAS NO:1312716-25-8
包装与价格:
包装价格(元)
5 mg电议
1 mL*10 mM(in DMSO)电议

产品介绍

产品描述

Scutebarbatine W can inhibit nitric oxide production efficiently with IC50 values of lower than 50 μM, it may have potential effects on the reduction of neuroinflammation.

体外活性

The arial parts of Scutellaria barbata D. Don (Lamiaceae) efficiently inhibited NO production in BV2 microglial cells, and the active constituents were further isolated based on activity-guided isolation using silica-gel column chromatography, RP-C18 MPLC and prep-HPLC. As the results, 2 flavonoids including 6-methoxynaringenin (1) and 6-O-methylscutellarein (5), and 6 neo-clerodane diterpenes such as Scutebarbatine W (2), scutebatas B (3), scutebarbatine B (4), scutebarbatine A (6), 6-O-nicotinolylscutebarbatine G (7) and Scutebarbatine X (8) were isolated. The structures of these compounds were elucidated based on NMR and MS data, and the comparison of literature values.

Cas No.

1312716-25-8

分子式

C33H37NO8

分子量

575.65

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years