KRM-III is a potent and orally active T-cell antigen receptor (TCR) inhibitor. KRM-III inhibits TCR- and phorbol myristate acetate/ionomycin-induced activation of nuclear factor of activated T cells (NFAT) and T-cell proliferation with an IC50 of ~5 μM. Anti-inflammatory activity[1].

79220-94-3

C15H12N2S

252.33

DMSO:100 mg/mL (396.31 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years