Nrf2 activator-2 (compound O15) 是一种蛇床子素衍生物，一种有效的Nrf2激动剂，在 293 T 细胞中的EC50为 2.9 μM。Nrf2 activator-2有效抑制 Keap1 和 Nrf2 的相互作用，从而显示出对 Nrf2 的激活作用。Nrf2 activator-2 显示细胞中泛素化 Nrf2 水平显着降低。

Nrf2 activator-2 (compound O15), a Osthole derivative, is a potent Nrf2 agonist with an EC 50 of 2.9 μM in 293 T cells. Nrf2 activator-2 effectively inhibits the interaction between Keap1 and Nrf2, thus showing the activation effect on Nrf2. Nrf2 activator-2 shows a marked decrease in the level of ubiquitinated Nrf2 in cells [1].

C20H17BrO3

385.25

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years